A high quality service from experimental design to data generation.

At the Mary Lyon Centre at MRC Harwell, we are working to improve our understanding of human disease through the study of mouse models and providing mouse genetics services to scientists around the world. These services cover all aspects of preclinical disease modelling in mice, including mouse model generation, a wide array of phenotyping tests, and archiving and distribution services. We adhere to the highest welfare standards and are proactively committed to implementing the 3Rs for the benefit of mouse health and welfare, while also improving the quality of the scientific data generated.

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Enabling mouse genetics research for academia and industry

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Professional, responsive, and able to keep up with ever-changing demand and tight deadlines. When it comes to mouse research, you'll definitely get the 5-star treatment from the Mary Lyon Centre
- Cryopreservation of mouse sperm service

Advance is a purpose built, high-quality, scientific training centre

Advance will build on MRC Harwell’s strong reputation for providing engaging training courses in mouse genetics, genome editing, pathology, and cryopreservation. Dedicated to improving health and plays a leading role in training future research leaders across a range of biomedical, clinical and health disciplines.

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Free bespoke mouse models with GEMM

Submit an application to our yearly GEMM programme which allows researchers to apply for a freely generated mouse line by the Mary Lyon Centre. GEMM offers a comprehensive genome engineering service that can meet researchers’ specific requirements.

Apply to get a free mouse model

Jobs and prospects at the Mary Lyon Centre

Opportunities to grow and develop your skills and career at the Mary Lyon Centre

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Senior Molecular Biologist

Closing date: 19th May 2024

Physical Security and Continuity Officer

Closing date: 06th May 2024

Work Experience

Our work experience programme is a valuable opportunity for students to find out more about careers in biomedical science, gain an insight into life in…

Catch up on the latest news to come out of the Mary Lyon Centre

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25 March 2024

Long-read sequencing provides faster and more comprehensive characterisation for genome editing

The MLC’s Molecular and Cellular Biology team, led by Lydia Teboul, have piloted how Oxford Nanopore Technology long-read sequencing allows…

22 March 2024

Citizen Science and Home Cage Monitoring: a steep learning curve with useful data acquired and insights gained

18 March 2024

Shining a light on an overlooked animal welfare issue

23 February 2024

Supporting career progression for technicians

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