Methods Development

The MLC contributes to the development of new techniques and research methods in areas such as animal husbandry and welfare, phenotyping of mutant lines, and mouse pathology. We are also at the forefront of improvements to technologies such as CRISPR and the latest imaging techniques.

Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants

Codner, G. F., Mianne, J., Caulder, A., Loeffler, J., Fell, R., King, R., Allan, A. J., Mackenzie, M., Pike, F. J., McCabe, C. V., Christou, S., Joynson, S., Hutchison, M., Stewart, M. E., Kumar, S., Simon, M. M., Agius, L., Anstee, Q. M., Volynski, K. E., Kullmann, D. M., Wells, S., Teboul, L.

(2018) , BMC Biol , 16 , 70



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The trouble with collective nouns for genome editing

Wells, S., Joly, J. S.

(2017) , Mamm Genome , 28 , 365-366


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Sharing mutations: are biobanks still required in the post-CRISPR/Cas9 era?

Kenyon, J., Fray, M. D.

(2017) , Mamm Genome , 28 , 383-387


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Phenotyping first-generation genome editing mutants: a new standard?

Teboul, L., Murray, S. A., Nolan, P. M.

(2017) , Mamm Genome , 28 , 377-382


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Introduction to Mammalian Genome Special Issue: Genome Editing

Teboul, L., Herault, Y., Smith, C., Whitelaw, B.

(2017) , Mamm Genome , 28 , 235-236


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