Methods Development
The MLC contributes to the development of new techniques and research methods in areas such as animal husbandry and welfare, phenotyping of mutant lines, and mouse pathology. We are also at the forefront of improvements to technologies such as CRISPR and the latest imaging techniques.
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants
Codner, G. F., Mianne, J., Caulder, A., Loeffler, J., Fell, R., King, R., Allan, A. J., Mackenzie, M., Pike, F. J., McCabe, C. V., Christou, S., Joynson, S., Hutchison, M., Stewart, M. E., Kumar, S., Simon, M. M., Agius, L., Anstee, Q. M., Volynski, K. E., Kullmann, D. M., Wells, S., Teboul, L.
The trouble with collective nouns for genome editing
Wells, S., Joly, J. S.
Sharing mutations: are biobanks still required in the post-CRISPR/Cas9 era?
Kenyon, J., Fray, M. D.
Phenotyping first-generation genome editing mutants: a new standard?
Teboul, L., Murray, S. A., Nolan, P. M.
Introduction to Mammalian Genome Special Issue: Genome Editing
Teboul, L., Herault, Y., Smith, C., Whitelaw, B.