Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring
Gaspar, R. S., Unsworth, A. J., Al-Dibouni, A., Bye, A. P., Sage, T., Stewart, M., Wells, S., Cox, R. D., Gibbins, J. M., Sellayah, D., C, E. Hughes
Loss of O-GlcNAcase catalytic activity leads to defects in mouse embryogenesis
Muha, V., Authier, F., Szoke-Kovacs, Z., Johnson, S., Gallagher, J., McNeilly, A., McCrimmon, R. J., Teboul, L., van Aalten, D. M. F.
Ap2s1 mutation causes hypercalcaemia in mice and impairs interaction between calcium-sensing receptor and adaptor protein-2
Hannan, F. M., Stevenson, M., Bayliss, A. L., Stokes, V. J., Stewart, M., Kooblall, K. G., Gorvin, C. M., Codner, G., Teboul, L., Wells, S., Thakker, R. V.
A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits
Cleverley, K., Lee, W. C., Mumford, P., Collins, T., Rickman, M., Cunningham, T. J., Cleak, J., Mianne, J., Szoke-Kovacs, Z., Stewart, M., Teboul, L., Maduro, C., Wells, S., Wiseman, F. K., Fisher, E. M. C.
Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism
Gaynor, K. U., Grigorieva, I. V., Mirczuk, S. M., Piret, S., Kooblall, K. G., Stevenson, M., Rizzoti, K., Bowl, M. R., Nesbit, M. A., Christie, P. T., Fraser, W. D., Hough, T., Whyte, M. P., Lovell-Badge, R., Thakker, R.