ADVANCE training centre


ADVANCE training centre
MRC Harwell


The Advance Team
+44 (0)1235 841438

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Mouse Genetics and Colony Management for Researchers



Feb 26 - 28 2024


10:00 am - 5:00 pm



Cost is inclusive of accommodation

This course explores more complex genetic topics, including multiple allele crosses, complex disease models and will inform breeding strategies and experimental design rather than give a complete guide to the molecular biology. Our team of experienced trainers will support you to examine how different modifications lead to different breeding strategies, the importance of genetic consistency and integrity and different modes of inheritance. There will be multiple workshops throughout the course and a focus on troubleshooting unexpected issues when looking after Genetically Altered (GA) mouse lines.

Who is this for?

  • Colony Managers
  • Researchers
  • PhD Students

After the course, you will be able to:

  • Understand genetic drift and how to maintain the genetic integrity of simple and complex GA lines
  • Understand GA nomenclature and why it is important
  • Predict the outcomes of genetic crosses involving multiple alleles, including chromosomal linkage and sex-linked genes
  • Perform multiple allele inheritance and breeding calculations
  • Understand the fundamentals of different methods that give rise to GA mouse strains
  • Troubleshoot breeding and colony maintenance issues
  • Know the basics of breeding conditional transgenic models
  • Discuss blinding and randomising GA experiments

The event is finished.

  • Since taking the course last spring I took your advice and have changed the way I am breeding to maintain our colony. This has a huge positive impact on not only the amount of cages in use, cost savings including genotyping, but of course also the 3Rs.

    20th Mar 2019

  • Thank you for the course. It absolutely answered the areas I was looking to know more about. Your in depth knowledge and expertise shone through. Plus, the course delivery was very engaging. I will definitely be recommending the course to my colleagues.

    24th Oct 2019

  • I just wanted to say thank you for the course and it was a pleasure to meet you both. We found the course very useful and informative.

    24th Oct 2019

    Submit to register for: Mouse Genetics and Colony Management for Researchers