Custom Allele Conversion

Our custom allele conversion service helps reduce the need to maintain in-house colonies of Cre/Flp deleter mice, enabling you to create new mouse models.

Support for mouse genome modification

The Cre/loxP and Flp-FRT systems provide valuable methods for tissue-specific modification of the mouse genome. To reduce the need for Cre or Flp deleter mice we use a permeable Cre method or inject Flp RNA to drive gene conversion in IVF-generated embryos.

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