A high quality service from experimental design to data generation.

At the Mary Lyon Centre at MRC Harwell, we are working to improve our understanding of human disease through the study of mouse models and providing mouse genetics services to scientists around the world. These services cover all aspects of preclinical disease modelling in mice, including mouse model generation, a wide array of phenotyping tests, and archiving and distribution services. We adhere to the highest welfare standards and are proactively committed to implementing the 3Rs for the benefit of mouse health and welfare, while also improving the quality of the scientific data generated.

More about the MLC

Enabling mouse genetics research for academia and industry

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Professional, responsive, and able to keep up with ever-changing demand and tight deadlines. When it comes to mouse research, you'll definitely get the 5-star treatment from the Mary Lyon Centre
- Cryopreservation of mouse sperm service

Advance is a purpose built, high-quality, scientific training centre

Advance will build on MRC Harwell’s strong reputation for providing engaging training courses in mouse genetics, genome editing, pathology, and cryopreservation. Dedicated to improving health and plays a leading role in training future research leaders across a range of biomedical, clinical and health disciplines.

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Free bespoke mouse models with GEMM

Submit an application to our yearly GEMM programme which allows researchers to apply for a freely generated mouse line by the Mary Lyon Centre. GEMM offers a comprehensive genome engineering service that can meet researchers’ specific requirements.

Apply to get a free mouse model

Jobs and prospects at the Mary Lyon Centre

Opportunities to grow and develop your skills and career at the Mary Lyon Centre

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Animal Technician

Closing date: 02nd June 2024

Phenotyping Technician

Closing date: 02nd June 2024

IT Service Desk Team Lead

Closing date: 09th June 2024

Work Experience

Our work experience programme is a valuable opportunity for students to find out more about careers in biomedical science, gain an insight into life in…

Catch up on the latest news to come out of the Mary Lyon Centre

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23 April 2024

Joint appointment at the Francis Crick Institute for our Director, Sara Wells 

Dr Sara Wells, Director of the Mary Lyon Centre at MRC Harwell (MLC), is now the Chief Biological Resources Facility…

5 April 2024

As a family, we stick together for a long time

25 March 2024

Long-read sequencing provides faster and more comprehensive characterisation for genome editing

22 March 2024

Citizen Science and Home Cage Monitoring: a steep learning curve with useful data acquired and insights gained

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